Oxford married (2nd) about 1406 or 1407 Alice Sergeaux (c.1386 - 18 May 1452), the widow of Guy St Aubyn of St Erme, Cornwall, and daughter of Sir Richard Sergeaux of Colquite, Cornwall by his second wife, Philippe (d. 18 May 1452), the daughter and co-heiress of Sir Edmund de Arundel,[10] who had been bastardized by the annulment in 1344 of the marriage of his parents, Richard Fitzalan, 10th Earl of Arundel and Isabel Despenser.[11] They had three sons:
John de Vere, 12th Earl of Oxford.
Sir Robert Vere (1410-1461), of Haccombe, Devon, who married Joan Courtenay (d. before 3 August 1465), daughter of Sir Hugh Courtenay by Philippa Archdekne, and widow of Sir Nicholas Carew (d. before 20 April 1448). Sir Robert Vere and Joan Courtenay had one son, John Vere (d. before 15 March 1488), who married Alice Colbroke, and by her was father of John de Vere, 15th Earl of Oxford.[12]
Sir Richard Vere, who married Margaret Percy (d. 22 September 1464), widow of Henry Grey, 6th Baron Grey of Codnor (d. 17 July 1444), and daughter and co-heiress of Sir Henry Percy 'of Atholl' of Harthill, Yorkshire, and his wife Elizabeth Bardolf, daughter of William Bardolf, 4th Baron Bardolf by Agnes Poynings.[13]