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Male Isaac Landon Click to view Isaac Landon in the family tree

Isaac was born on August 4th, 1776.1   Isaac's father was Thomas Landon and his mother was Experience Johnson.  His paternal grandparents were David Landon and Mary Osborn. He had four brothers named Thomas, Ethan, Edmund and Horace.  He was the second oldest of the five children.1 

1 phelps.FTW @ Tree #1309
Further sources/citations:
World Family Tree Vol. 3, Ed. 1 @ Tree #3455, 3455.ftw