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Male Isaac Knowles Click to view Isaac Knowles in the family tree

Isaac was born about 1685 in Woodbury, Litchfield Co., Connecticut.1   Isaac's father was Eleazer Knowles and his mother was Mary Unknown.  His paternal grandparents were Thomas Knowles and Elizabeth Newman. He had three brothers and three sisters, named Thomas, Samuel, Isaac, Elizabeth, Anna and Mary.  He died in Woodbury, Litchfield Co., Connecticut.1 

1 basel.FTW
Further source/citation:
World Family Tree Vol. 9, Ed. 1 @ Tree #2571