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Male Isaac Howe Click to view Isaac Howe in the family tree

Isaac was born on December 20th, 1781.1   Isaac's father was Timothy Howe and his mother was Keziah Powers.  His paternal grandfather was Martin Howe. He had three brothers and two sisters, named Martin, Timothy, P. William, Phoebe and Polly.  He was the oldest of the six children.  He died at the age of 80 in 1861.1 

1 basel.FTW
Further source/citation:
World Family Tree Vol. 9, Ed. 1 @ Tree #2571