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Male Isaac Frye Click to view Isaac Frye in the family tree

1   Isaac's father was William Frye and his mother was Nancy Spaid.  His maternal grandparents were George Nicholas Spaid(Spaht) and Elizabeth Cale. He had two brothers and two sisters, named George, James, Margaret Jane Frye and Elizabeth Frye.1 

1 phelps.FTW
Further source/citation:
World Family Tree Vol. 2, Ed. 1 @ Tree #5354