Diego Colon 
Diego's father was Cristoforo Colombo and his mother is Filipa Perestrello. He was an only child. He died on February 23rd, 1527.General Notes
SOURCES: "Ancestors/Descendants of Royal Lines" (Contributors: Manuel Abranches de Soveral, Reynaud de Paysac, H.R. Moser <Burke Peerage>), O.Guionneau, E. Polti, A.Terlinden <Genealogy of the existing British Peerage, 1842, and E. Lodge>)
They had a daughter named Isabel.
