Francisco De Orozco Y Ayala

Francisco De Orozco Y's father was Jeronimo De Orozco Y De La Guerra and his mother was Juana De Ayala Y Colindres.  His paternal grandparents were Francisco De Orozco and Beatriz De La Guerra; his maternal grandparents were Juan Lopez De Ayala and Catalina Colindres Puerta.  He was an only child.

They had a daughter named Lorenza De Orozco Y De Los.