Isabel was born on May 31st, 1326.1 Isabel's father was John De Moels and her mother was Joan Lovell. Her paternal grandparents were John De Moels and Grey; her maternal grandparents were Richard Lovell and Muriel Soulis. She had a sister named Muriel. She was the younger of the two children. She died at the age of 23 on July 19th, 1349.1