William was born on April 22nd, 1522 in London, England.1 William's father was James Gresham. His paternal grandfather was John Gresham and his paternal grandmother is Margaret. He had three brothers and a sister, named William, John, William and Susan. He was the oldest of the five children. He died at the age of 56 on June 20th, 1578 in London, England.1