Johannes Comnenus
Johannes was born about 1018 in Constantinople, Turkey.  He died in 1067.

 Anna Dalassena
Anna was born about 1023.  Anna is no longer alive.

 Alexius I Comnenus
Alexius I was born about 1048 in Constantinople, Constantinople, Turkey.  He died in 1118.

 Isaac Comnenus
Isaac was born about 1050.