Francisco I. Luiz Portugal, de & Brites de Vilhena Menezes, de

Francisco I. Luiz and Brites de Vilhena were married in a religious ceremony in 1506. They had a daughter named Guiomar.

Children
- Guiomar Portugal, de
  Guiomar was born in 1508. She died at the age of 77 in 1585. She was buried in Vidigueira.