Louis XIII, King of France 27 September 1601 14 May 1643 Married Anne of Austria (1601–1666) in 1615. Two sons survived to adulthood.
Elisabeth, Queen of Spain 22 November 1602 6 October 1644 Married Philip IV, King of Spain (1605–1665) in 1615. A son and a daughter survived to adulthood.
Christine, Duchess of Savoy 10 February 1606 27 December 1663 Married Victor Amadeus I, Duke of Savoy (1587–1637) in 1619. One son and three daughters survived to adulthood.
Nicholas Henri, Duke of Orléans 16 April 1607 17 November 1611 Died young.
Gaston, Duke of Orléans 25 April 1608 2 February 1660 Married (1) Marie de Bourbon (1605–1627) in 1626. 1 daughter survived to adulthood.
Married (2) Marguerite of Lorraine (1615–1672) in 1632. Three daughters survived to adulthood.
Henrietta Maria, Queen of England 25 November 1609 10 September 1669 Married Charles I, King of England (1600–1649) in 1625. Three sons and two daughters survived to adulthood.