Ralph Leigh died 6 November 1509,[24] and Joyce Culpeper married Lord Edmund Howard, and by him had three sons and three daughters:[25]
Henry Howard, esquire.
Sir Charles Howard, who incurred Henry VIII's displeasure for having fallen in love with Margaret Douglas, later Countess of Lennox, while Margaret was serving as first lady of honour to Charles' sister, Queen Catherine Howard.[26]
Sir George Howard (c. 1519 - 1580).
Margaret Howard (d. 10 October 1571), who married Sir Thomas Arundell of Wardour Castle, beheaded on Tower Hill on 26 February 1552, and by him had two sons, Sir Matthew Arundell (d. 24 December 1598) of Wardour Castle, and Charles Arundell (d. 1587), and two daughters, Dorothy, who married Sir Henry Weston, and Jane, who married Sir William Bevyle.[27]
Catherine Howard, who married Henry VIII, but had no issue.
Mary Howard, who married Edmund Trafford.
Joyce Culpeper was living in 1527.[28] She is thought to have died about 1528.[29]