Isaac II Angelus of Byzantium
Isaac II Angelus of was born in 1155 in Constantinople, Byzantium Empire.  He died at the age of 49 on April 12th, 1204 in Constantinople, Byzantium Empire.

 Margaret Maria

 Irene of Byzantium
Irene of was born before 1201.  She died on August 27th, 1208.

 Alexius IV of Byzantium
Alexius IV of was born before 1204.  He died in 1204.