In 1851, Alice Middleton (aged 1), born New Mills, Derbyshire was the youngest of 5 children of Charles Middleton (50) and Elizabeth (42, born Prestwich). Elizabeth and Johns wife Alice Kenyon were sisters from Prestwich.
In 1861, Alice Middleton, niece, aged 11 was living with John Mather (and assumed cousin Sarah Barlow, also 11).
In 1871 Alice Middleton (21), born Mills, Derbyshire and Sarah Barlow (21) were still with John Mather at Church Street, Middleton.