Edward Cromwell
Edward was born about 1562.  He died in 1607 in Ireland.

 Frances Rugge
Frances was born about 1565.  She died before November 30th, 1631.

 Anne Cromwell
Anne was born about 1588.  She died on July 11th, 1636.

 Thomas Cromwell
Thomas was born on June 11th, 1594.  He died at the age of 59 in 1653.