Isaac II Angelus De Bizancio
Isaac II was born in 1155.  He died at the age of 49 on April 12th, 1204.

 Irène Comnène
Irène was born in 1154.  She died before 1190.

 Irène Ange
Irène was born in 1172.  She died at the age of 36 on August 27th, 1208.