poss Charles Powers
poss Charles was born before 1748 in maybe VA.  He died after 1790.

 Hannah
Hannah was born after 1790.  She died in poss Nelson Co. Kentucky.

 Isaac H. Powers
Isaac H. was born about 1765 in poss. Harrison Co. VA or W VA.  He died on July 30th, 1834 in Warrick County,Indiana.

 John Powers
He died on September 18th, 1827 in Ohio County,Kentucky.